Warren Lewis




Selected Publications 

2013

Gilbert, N.M.; Lewis, WG; Lewis, AL.  Clinical Features of Bacterial Vaginosis in a Murine Model of Vaginal Infection with Gardnerella vaginalis. PLoS One. 2013;8(3):e59539. doi: 10.1371/journal.pone.0059539. Epub 2013 Mar 19.


Lewis, WG; Robinson, LS; Gilbert, N.M.; Perry, JC; Lewis, AL. Degradation, Foraging and Depletion of Mucus Sialoglycans by the Vagina-Adapted Actinobacterium Gardnerella vaginalis. J. Biol. Chem. 2013 Apr 26;288(17):12067-79. doi: 10.1074/jbc.M113.453654. Epub 2013 Mar 11.

 

2012

Lewis AL, Lewis WG. Host Sialoglycans and Bacterial Sialidases: A Mucosal PerspectiveCell Microbiol. 2012 Apr 23. doi: 10.1111/j.1462-5822.2012.01807.x.PMID: 22519819

Lewis, WG; Robinson, LS; Perry, JC; Peipert, JF; Allsworth, JE; Lewis, AL.  Hydrolysis of the Secreted Sialoglycoprotein Immunoglobulin A (IgA) in Ex Vivo and In Vitro Models of Bacterial Vaginosis. J. Biol. Chem. 2012. Jan 13;287(3):2079-89. 


2011

Kline, K.A.; Schwartz, D.J.; Lewis, W.G.; Hultgren, S.J.; Lewis, A.L. Immune Activation and Suppression by Group B Streptococcus in a Murine Model of Urinary Tract Infection. Infect Immun. 2011 Sep;79(9):3588-95. 


2010

Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X, Garcia M, Peters EC, Etchegaray JP, Traver D, Schultz PG, Kay SA. High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase. PLoS Biol. 2010 Dec 14; 8(12):e1000559.


2009

Hirota T, Lewis WG, Liu AC, Lee JW, Schultz PG, Kay SA. A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta. Proc Natl Acad Sci U S A. 2008; 105(52):20746-51.


2005

Sen Gupta S, Kuzelka J, Singh P, Lewis WG, Manchester M, Finn MG. Accelerated bioorthogonal conjugation: a practical method for the ligation of diverse functional molecules to a polyvalent virus scaffold. Bioconjug Chem. 2005; 16(6):1572-9.


2004

Lewis WG, Magallon FG, Fokin VV, Finn MG. Discovery and characterization of catalysts for azide-alkyne cycloaddition by fluorescence quenching. J Am Chem Soc. 2004; 126(30):9152-3.

Meng JC, Averbuj C, Lewis WG, Siuzdak G, Finn MG. Cleavable linkers for porous silicon-based mass spectrometry. Angew Chem Int Ed Engl. 2004; 43(10):1255-60. 


2002

Lewis WG, Green LG, Grynszpan F, Radić Z, Carlier PR, Taylor P, Finn MG, Sharpless KB. Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks. Angew Chem Int Ed Engl. 2002; 41(6):1053-7.